Miriam Segura-Totten, Ph.D.
Harry B. Forester Eminent Scholars Chair
Office: Health and Natural Sciences 414, Dahlonega
Areas of Expertise: Cell Biology, Molecular biology, Scholarship of Teaching and Learning
- BIOL 1101 Biology: A Human Perspective
- BIOL1107 Principles of Biology I
- BIOL 3240 Cell Biology
- BIOL 4x26 Cell Biology of the Nucleus
- HNRS 3000 Honors Research Methods
- Ph.D., Biochemistry, Cell & Molecular Biology, Johns Hopkins School of Medicine, 2003
- A.B., Molecular Biology, Princeton University, 1998
Dr. Segura-Totten's research, which has been funded by the National Institutes of Health, the American Association for the Advancement of Science, and Merck, is focused on understanding the structure and function of vertebrate nuclei, in particular how nuclei assemble and disassemble during cell division. She is also interested in elucidating how mutations in genes that encode for certain nuclear proteins can lead to disease in humans.
Dr. Segura-Totten is currently studying how specific educational interventions affect the development of critical thinking skills in students.
Segura-Totten M, Dalman D.E. 2013. The CREATE method does not result in greater gains in critical thinking than a more traditional method of analyzing the primary literature. J Microbiol Biol Educ. 14(2), 166-75.
Segura-Totten, M. 2012. Initiating Undergraduate Research Through a Task Force. In J. Kinkaid and L. Blockus (Ed.), Undergraduate Research Offices & Programs: Models & Practices (pp. 214-219). Washington, DC: Council on Undergraduate Research.
Segura-Totten, M. 2012. Jim and the forgotten embryos: a case study on stem cell-based therapy. Retrieved August 21, 2012, from http://sciencecases.lib.buffalo.edu/cs/collection/detail.asp?case_id=628&id=628
Tifft K, Segura-Totten M, Lee KK, and Wilson KL. 2006. BAF-Like: A proposed regulator of BAF. Exp Cell Res. 312, 478-87.
Segura-Totten M and Wilson KL. 2004. BAF: roles in chromatin, nuclear structure and retrovirus integration. Trends Cell Biol., 14: 261-6.
Liu J, Lee KK, Segura-Totten M, Neufeld E, Wilson KL, and Gruenbaum Y. 2003. MAN1 and emerin have overlapping function(s) essential for chromosome segregation and cell division in C. elegans. Proc. Natl. Acad. Sci. USA, 100:4598-603.
Segura-Totten M, Kowalski AK, Craigie R, and Wilson KL. 2002. Barrier-to-autointegration factor: major roles in chromatin decondensation and nuclear assembly. J. Cell Biol., 158:475-85.
Segura-Totten M and Wilson KL. 2001. Virology. HIV--breaking the rules for nuclear entry. Science, 294:1016-7.
Dr. Segura-Totten was born and raised in Puerto Rico, so she is fluent in both English and Spanish. She came to the U.S. to attend college and has since lived in several states on the east coast, as well as having traveled to Latin America and Europe. She loves to spend time with her husband and her son. She welcomes all students, especially those wishing to converse in Spanish or learn more about her culture and research, to contact her.