Back to Top
Skip to Site Search Skip to Utility Nav Skip to Top Nav Skip to Left Nav Skip to Content
Close Main Menu

Cell Biology Research

Dahlonega Campus

Alexandra Tremblay, Ph.D.

Main Research Goals

To determine mechanisms of immune cell regulation.

Potential Roles for Students

  • ELISA
  • Cell culture
  • Animal models
  • Cell activity assays
  • Microscopy

Relevant Publications

Bian Z, Shi L, Guo YL, Lv Z, Tang C, Niu S, Tremblay, A, et al. 2016. Cd47-Sirpα interaction and IL-10 constrain inflammation-induced macrophage phagocytosis of healthy self-cells. Proceedings of the National Academy of Sciences of the United States of America 113(37):E5434-43.

Gainesville Campus

Main Research Goals

The effect of natural agricultural products on the growth of cancer cells.

Potential Roles for Students

  • Tissue culture work
  • MTT assays
  • Western blotting
  • Immunohistochemistry
  • Bioinformatics

Relevant Publications

Rhodes, S., Short, S., Sharma, S., Kaur, R., & Jha, M. (2019). One-pot mild and efficient synthesis of [1,3]thiazino[3,2-a]indol-4-ones and their anti-proliferative activity. Org Biomol Chem, 17(16), 3914-3920.

Mittal K, Donthamsetty S, Kaur R, et al. 2017. Multinucleated polyploidy drives resistance to Docetaxel chemotherapy in prostate cancer. British Journal of Cancer 116(9):1186-1194.

Mittal K, Choi DH, Klimov S, Pawar S, Kaur R, et al. 2016. A centrosome clustering protein, KIFC1, predicts aggressive disease course in serous ovarian
adenocarcinomas. J Ovarian Res 18(9):17.

Shashidharamurthy R, Bozeman EN, Patel J, Kaur R, et al. 2012. Immunotherapeutic strategies for cancer treatment: A novel protein transfer approach for cancer vaccine development. Medicinal Research Reviews 32(6):1197-219.

Engelman JA, Chen L, Tan X, Crosby K, Guimaraes AR, Upadhyay R, Maira M, McNamara K, Perera SA, Song Y, Chirieac LR, Kaur R, et al. 2008. Effective use of PI3K and MEK inhibitors to treat mutant K-Ras G12D and PIK3CA H1047R murine lung cancers. Nat Med.14(12):1351-6.

Kaur R, Yuan X, Lu ML, Balk SP. 2008. Increased PAK6 expression in prostate cancer and identification of PAK6 associated proteins. Prostate 68(14):1510-6.

Main Research Goals

To model human diseases, such as infertility and neurodegeneration, in Drosophila melanogaster.

Potential Roles for Students

  • Bioinformatics
  • Genome editing
  • Western blotting
  • Immunofluorescence microscopy
  • Behavior assay

Relevant Publications

Hudson A, Parrott BB, Qian Y, Schulz C. 2013. A temporal signature of epidermal growth factor signaling regulates the differentiation of germline cells in testes of Drosophila melanogaster. PLoS One 8(8):e70678.

Qian Y, Ng CL, Schulz C. 2015. CSN maintains the germline cellular microenvironment and controls the level of stem cell genes via distinct CRLs in testes of Drosophila Melanogaster. Developmental Biology 398(1):68-79.

Qian Y, Dominado N, Zoller R, Ng C, et al. 2014. Ecdysone signaling opposes epidermal growth factor signaling in regulating cyst differentiation in the male gonad of Drosophila Melanogaster. Developmental Biology 394(2):217-27.

UNG follows Section 508 Standards and WCAG 2.0 for web accessibility. If you require the content on this web page in another format, please contact the ADA Coordinator.

Back to Top